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Myeloproliferative Neoplasms

 

The myeloproliferative neoplasms are a group of diseases that cause platelets, white blood cells and red blood cells to grow abnormally in the bone marrow. This may cause bleeding problems, anemia, infection, or fatigue. Myeloproliferative disorders include polycythemia vera, essential thrombocytosis, myelofibrosis, chronic myelogenous leukemia, and chronic eosinophilic leukemia. Over time some of the myeloproliferative neoplasms may become acute myeloid leukemia (AML).

Common chromosome changes:

BCR/ABL1 t(9;22)
FIPILI/PDGFRA 4q12 rearrangement
PDGFRB 5q33 rearrangement
FGFR1 8p12 rearrangement

Methodology: Fluorescent in Situ Hybridization (FISH) Analysis

Purpose: Confirmation of Clinical Diagnosis/Monitor During Treatment

Test Requisition: Cancer Requisition

Turn-around-time: 2-5 days

Specimen Requirements

Shipping Information

 

 


Contact Information
Genetics Laboratory
University of Oklahoma Health Sciences Center
1122 NE 13 Street, Suite 1400, Oklahoma City, OK 73104
Phone: (405) 271-3589 |Fax: (405) 271-7117 Email: Dr. Shibo Li

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