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FISH for +13, +18, +21, X/Y


Using FISH techniques, our laboratory can provide results within 24-48 hours for blood, amniotic fluid, and buccal swab specimens.  Receiving results quickly is invaluable, if for example, you are treating an infant with dysmorphic features and want to rule out Down syndrome, or you require confirmation for prenatal ultrasound findings for trisomy 13 or trisomy 18. The probes used in this assay have been approved by the FDA.

Methodology: Fluorescent in Situ Hybridization (FISH) Analysis

Purpose: Confirmation of Clinical Diagnosis/Prenatal Diagnosis

Down Syndrome ICD-10 Code Q90.9

Trisomy 13 ICD-10 Code Q91.7

Trisomy 18 ICD-10 Code Q91.3

Test Requisition: Cytogenetics Requisition

Turn-around-time: 24-48 hours for blood/amnio/buccal swab

Tissue samples require 3-4 weeks turn around time. Culturing of the cells provides better resolution for screening these types of specimens.

Specimen Requirements

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Contact Information
Genetics Laboratory
University of Oklahoma Health Sciences Center
1122 NE 13 Street, Suite 1400, Oklahoma City, OK 73104
Phone: (405) 271-3589 |Fax: (405) 271-7117 Email: Dr. Shibo Li

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