Pancreatic cancer refers to a malignant neoplasm originating from transformed cells arising in tissues that form the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The symptoms that lead to diagnosis depend on the location, the size, and the tissue type of the tumor.
The PALB2 gene contains the information to make the PALB2 protein. This protein works together with the BRCA2 protein to repair damaged DNA. The PALB2 protein is believed to stabilize the BRCA2 protein, allowing the BRCA2 protein to repair damaged DNA. It was recently discovered that 3-5% of patients with familial pancreatic cancer have inherited mutations in the PALB2 gene.
Purpose: Confirmation of Clinical Diagnosis/Carrier Testing
Methodology: Sequencing of entire coding region
Test Requisition: Sequencing Requisition
Specimen Requirements: 2-5 mL Blood- Lavender Top Tube
CPT Code: 81406 Cost: $540.00
Turn-around-time: 5 weeks
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