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FISH T-cell Acute Leukemia

 

Cancer of T-cells. Precursors to white blood cells are called blasts and are made by the bone marrow but in ALL the blasts are abnormal and do not develop into lymphocytes. Instead, the abnormal blasts or leukemic cells multiply rapidly and reduce the level of other types of blood cells such as red blood cells and platelets.

Common chromosome changes:

BCR/ABL t(9;22)(q34;q11.2)
MLL  11q23 rearrangement
TCR alpha/delta  14q11 rearrangement

Methodology: Fluorescent in Situ Hybridization (FISH) Analysis

Purpose: Confirmation of Clinical Diagnosis/Monitor During Treatment

ICD-10 Code: C91.00

Test Requisition: Cancer Requisition

Turn-around-time: 2-5 days

Specimen Requirements

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Contact Information
Genetics Laboratory
University of Oklahoma Health Sciences Center
1122 NE 13 Street, Suite 1400, Oklahoma City, OK 73104
Phone: (405) 271-3589 |Fax: (405) 271-7117 Email: Dr. Shibo Li

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