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Also called Y chromosome infertility and it is considered a diagnostic possibility when an otherwise healthy male is infertile. Patients with this deletion typically present with oligozoospermia (a subnormal number of sperm) or azoospermia (the absence of sperm). This condition is caused by a deletion or rearrangement of the long arm of the Y chromosome. Chromosome analysis or molecular studies may reveal the microdeletions of regions AZFa, AZFb, or AZFc of the Y chromosome.

Methodology: Polymerase chain reaction (PCR) test DNA for the presence of microdeletions of the Y chromosome (region AZFa, AZFb, and AZFc).

Purpose: Confirmation of Clinical Diagnosis

ICD-10 Code: Q98.6

Test Requisition: Molecular Requisition

CPT Code: 81403 Cost: $500.00 (Oklahoma Medicaid requires preauthorization for this test)

Turn-around-time: 21 days

Specimen Requirements

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Contact Information
Genetics Laboratory
University of Oklahoma Health Sciences Center
1122 NE 13 Street, Suite 1400, Oklahoma City, OK 73104
Phone: (405) 271-3589 |Fax: (405) 271-7117 Email: Dr. Shibo Li

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